In general, the formats of collagen wound dressing like the collagen sheet, sponge, film and particles can be applied in the various epidermal or dermal wounds such as burns, traumatic wounds, surgical wounds, chronic wounds, etc.
Collagen Sheet or Pad wound dressings are normally prepared by casting and freeze drying processes, and then different shapes or dimensions can be performed by using a specific casting mold. Collagen sheet wound dressing can be used as both temporary and permanent coverings for superficial wounds related to epidermal or dermal injury. During wound healing, the ability of cellular ingrowth within a collagen wound dressing depends on the pore size and porosity of its fibrous structure. Collagen sheet wound dressing is well-suitable for burns, ulcers and surgical wounds as they revealed rapid epithelialization and dense fibrosis tissue ingrowth in the subdermal layers.
Collagen Powders or Particles can be sprinkled sufficiently to cover the wound surface with irregular situation such as tunnelled wounds. Most importantly, collagen particles wound dressing can be mixed with normal saline to make a paste or a solution to be more easily applied to the wound.
Collagen topical gels when compared to wound dressing formed as a sheet or sponge, gel form materials are easier to add active components such as antibacterial agents. According to recent research, collagen gel wound dressings comprised of pure collagen, collagen blends with natural and/or synthetic polymers, or collagen blends with bioactives are required for better skin wound management due to wound type diversity and environmental complexity.
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