Evidence-Based Treatment Options In Diabetic Foot Ulcers (DFUs)

Advanced wound care technology has come a long way in treating chronic wounds. However, diabetic foot ulcers (DFUs) can be difficult to treat, and not every patient should be allocated the same treatment plan. Traditional approaches are considerably less effective than patient-centered care. Understanding each patient’s unique demands as well as the pathophysiology of diabetic wound chronicity are key components in the therapy of diabetic foot ulcers (DFUs). The primary goal should ideally be wound closure, with secondary goals including recurrence avoidance. To achieve both goals, we must incorporate continual education and clinical support into our efforts. To provide their patients with the most tailored advanced therapy possible, healthcare practitioners should stay up to date on the most recent evidence-based research and methods.

Offloading Methods in DFUs

Offloading is critical for the healing of diabetic foot ulcers. In diabetics with neuropathy, pain responses are inhibited. Reduced shear and pressure tissue stresses are critical in assisting healing. Offloading therapy treatment options include therapeutic shoes, custom orthotics, post-operative shoes or sandals, pad and protect dressings, removable cast boots (RCB), and total contact casts.

Wound Bed Preparation

During wound bed preparation, a noncytotoxic solution should be used for the wound cleansing technique. Applying topical antimicrobial and antibacterial agents restores bacterial control in chronic wounds. This reduces the number of present bacteria. Bioburden, also known as biofilm, is a substance that impedes healing and increases the likelihood of infection.

Debridement Options

One or more of the five debridement methods may be required in achieving good wound bed preparation.. Many debridement treatments can be used sequentially to provide the best healing results. The debridement methods remove dead, injured, or contaminated tissue to accelerate wound chronicity toward closure. Biologic, enzymatic, autolytic, mechanical, and surgical means of debridement are methods that can be used; however, the choice of method depends on factors such as the type of wound, its location, and the wound assessment findings.

Advanced Wound Care Dressings with Collagen

DFUs exhibit a protracted inflammatory response as well as extracellular matrix (ECM) abnormalities. Collagen dressing technologies assist and aid in the formation of a scaffolding matrix that regulates extracellular components, allowing chronic wounds to heal more quickly and effectively.

Growth Factors

With adequate blood flow, becaplermin 0.01 percent is a recombinant human platelet-derived growth factor (rhPDGF-BB) approved by the FDA for the treatment of full-thickness diabetic ulcers on the lower extremities. In addition to promoting and supporting the wound healing process, this topical agent also stimulates wound healing..

Cellular And Tissue-Based Products (CTPs)

Cellular and tissue-based products (CTPs) are advanced therapies that use human or animal cells, tissues, or cellular and tissue-based products to promote wound healing. They are increasingly utilized in the management of diabetic foot ulcers (DFUs) to accelerate the healing process.

Important Notice: The views and opinions stated in this blog are exclusively those of the author and do not reflect iWound Global, iWound Care USA, Inc., its affiliates, or partner companies. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment.